Phosphine-Catalysed Cyclisation of beta-Hydroxy-alpha,alpha-Difluoroynones
2-Benzylidene-4,4-difluorodihydrofuran-3(2H)-ones were synthesised in 58-86% yield via phosphine-promoted cyclisation of β-hydroxy-α, α-difluoroynones. The benzylidene group was found to be a suitable masked carbonyl group, thereby allowing for the validation of a novel route to 3,3-difluoro-2-hydro...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2009
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