Putidaredoxin binds to the same site on cytochrome P450cam in the open and closed conformation

Cytochrome P450 CYP101A1 (P450cam) hydroxylates camphor by receiving two distinct electrons from its unique reductase, putidaredoxin (Pdx). Upon binding ferric P450cam, Pdx is now known to trigger a conformational change in the enzyme. This Pdx-induced conversion may provide the trigger to coordinat...

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Bibliographic Details
Main Authors: Liou, S, Myers, W, Oswald, J, Britt, R, Goodin, D
Format: Journal article
Language:English
Published: American Chemical Society 2017