RNA polymerase II phosphorylated on CTD serine 5 interacts with the spliceosome during co-transcriptional splicing
The highly intronic nature of protein coding genes in mammals necessitates a co-transcriptional splicing mechanism as revealed by mNET-seq analysis. Immunoprecipitation of MNase-digested chromatin with antibodies against RNA polymerase II (Pol II) shows that active spliceosomes (both snRNA and prote...
Главные авторы: | , , , , , |
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Формат: | Journal article |
Язык: | English |
Опубликовано: |
Elsevier
2018
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