STUDIES ON THE MECHANISM OF DEACETOXY DEACETYLCEPHALOSPORIN-C SYNTHASE USING CYCLOPROPYL SUBSTITUTED CEPHALOSPORIN PROBES
Cyclopropyl substituted cephalosporin analogues were prepared and evaluated as substrates for the Fe II/α-ketoglutarate dependent oxygenase, DAOC-DAC synthase; the first example of catalytic product formation from a Cyclopropyl ring cleavage pathway by an α-ketoglutarate dependent oxygenase is repor...
| Main Authors: | , , , , , , , , |
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| Format: | Journal article |
| Published: |
1991
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