STUDIES ON THE MECHANISM OF DEACETOXY DEACETYLCEPHALOSPORIN-C SYNTHASE USING CYCLOPROPYL SUBSTITUTED CEPHALOSPORIN PROBES
Cyclopropyl substituted cephalosporin analogues were prepared and evaluated as substrates for the Fe II/α-ketoglutarate dependent oxygenase, DAOC-DAC synthase; the first example of catalytic product formation from a Cyclopropyl ring cleavage pathway by an α-ketoglutarate dependent oxygenase is repor...
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Bibliographic Details
| Main Authors: |
Baldwin, J,
Adlington, R,
Crouch, N,
Keeping, J,
Leppard, S,
Pitlik, J,
Schofield, C,
Sobey, W,
Wood, M |
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| Format: | Journal article
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| Published: |
1991
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