STUDIES ON THE MECHANISM OF DEACETOXY DEACETYLCEPHALOSPORIN-C SYNTHASE USING CYCLOPROPYL SUBSTITUTED CEPHALOSPORIN PROBES
Cyclopropyl substituted cephalosporin analogues were prepared and evaluated as substrates for the Fe II/α-ketoglutarate dependent oxygenase, DAOC-DAC synthase; the first example of catalytic product formation from a Cyclopropyl ring cleavage pathway by an α-ketoglutarate dependent oxygenase is repor...
| Main Authors: | , , , , , , , , |
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| Format: | Journal article |
| Published: |
1991
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| _version_ | 1826275591284850688 |
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| author | Baldwin, J Adlington, R Crouch, N Keeping, J Leppard, S Pitlik, J Schofield, C Sobey, W Wood, M |
| author_facet | Baldwin, J Adlington, R Crouch, N Keeping, J Leppard, S Pitlik, J Schofield, C Sobey, W Wood, M |
| author_sort | Baldwin, J |
| collection | OXFORD |
| description | Cyclopropyl substituted cephalosporin analogues were prepared and evaluated as substrates for the Fe II/α-ketoglutarate dependent oxygenase, DAOC-DAC synthase; the first example of catalytic product formation from a Cyclopropyl ring cleavage pathway by an α-ketoglutarate dependent oxygenase is reported. |
| first_indexed | 2024-03-06T23:01:04Z |
| format | Journal article |
| id | oxford-uuid:6223aea7-a9a1-4a53-abd3-32cab69ae44b |
| institution | University of Oxford |
| last_indexed | 2024-03-06T23:01:04Z |
| publishDate | 1991 |
| record_format | dspace |
| spelling | oxford-uuid:6223aea7-a9a1-4a53-abd3-32cab69ae44b2022-03-26T18:04:23ZSTUDIES ON THE MECHANISM OF DEACETOXY DEACETYLCEPHALOSPORIN-C SYNTHASE USING CYCLOPROPYL SUBSTITUTED CEPHALOSPORIN PROBESJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:6223aea7-a9a1-4a53-abd3-32cab69ae44bSymplectic Elements at Oxford1991Baldwin, JAdlington, RCrouch, NKeeping, JLeppard, SPitlik, JSchofield, CSobey, WWood, MCyclopropyl substituted cephalosporin analogues were prepared and evaluated as substrates for the Fe II/α-ketoglutarate dependent oxygenase, DAOC-DAC synthase; the first example of catalytic product formation from a Cyclopropyl ring cleavage pathway by an α-ketoglutarate dependent oxygenase is reported. |
| spellingShingle | Baldwin, J Adlington, R Crouch, N Keeping, J Leppard, S Pitlik, J Schofield, C Sobey, W Wood, M STUDIES ON THE MECHANISM OF DEACETOXY DEACETYLCEPHALOSPORIN-C SYNTHASE USING CYCLOPROPYL SUBSTITUTED CEPHALOSPORIN PROBES |
| title | STUDIES ON THE MECHANISM OF DEACETOXY DEACETYLCEPHALOSPORIN-C SYNTHASE USING CYCLOPROPYL SUBSTITUTED CEPHALOSPORIN PROBES |
| title_full | STUDIES ON THE MECHANISM OF DEACETOXY DEACETYLCEPHALOSPORIN-C SYNTHASE USING CYCLOPROPYL SUBSTITUTED CEPHALOSPORIN PROBES |
| title_fullStr | STUDIES ON THE MECHANISM OF DEACETOXY DEACETYLCEPHALOSPORIN-C SYNTHASE USING CYCLOPROPYL SUBSTITUTED CEPHALOSPORIN PROBES |
| title_full_unstemmed | STUDIES ON THE MECHANISM OF DEACETOXY DEACETYLCEPHALOSPORIN-C SYNTHASE USING CYCLOPROPYL SUBSTITUTED CEPHALOSPORIN PROBES |
| title_short | STUDIES ON THE MECHANISM OF DEACETOXY DEACETYLCEPHALOSPORIN-C SYNTHASE USING CYCLOPROPYL SUBSTITUTED CEPHALOSPORIN PROBES |
| title_sort | studies on the mechanism of deacetoxy deacetylcephalosporin c synthase using cyclopropyl substituted cephalosporin probes |
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