STUDIES ON THE MECHANISM OF DEACETOXY DEACETYLCEPHALOSPORIN-C SYNTHASE USING CYCLOPROPYL SUBSTITUTED CEPHALOSPORIN PROBES

STUDIES ON THE MECHANISM OF DEACETOXY DEACETYLCEPHALOSPORIN-C SYNTHASE USING CYCLOPROPYL SUBSTITUTED CEPHALOSPORIN PROBES

Cyclopropyl substituted cephalosporin analogues were prepared and evaluated as substrates for the Fe II/α-ketoglutarate dependent oxygenase, DAOC-DAC synthase; the first example of catalytic product formation from a Cyclopropyl ring cleavage pathway by an α-ketoglutarate dependent oxygenase is repor...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Baldwin, J, Adlington, R, Crouch, N, Keeping, J, Leppard, S, Pitlik, J, Schofield, C, Sobey, W, Wood, M
Format: Journal article
Veröffentlicht: 1991

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