New treatments compared to established treatments in randomized trials.

BACKGROUND: The proportion of proposed new treatments that are 'successful' is of ethical, scientific, and public importance. We investigated how often new, experimental treatments evaluated in randomized controlled trials (RCTs) are superior to established treatments. OBJECTIVES: Our mai...

Full description

Bibliographic Details
Main Authors: Djulbegovic, B, Kumar, A, Glasziou, P, Perera, R, Reljic, T, Dent, L, Raftery, J, Johansen, M, Di Tanna, G, Miladinovic, B, Soares, H, Vist, G, Chalmers, I
Format: Journal article
Language:English
Published: 2012