Fundamental importance of Na+-Ca2+ exchange for the pacemaking mechanism in guinea-pig sino-atrial node.

Na+-Ca2+ exchange (NCX) current has been suggested to play a role in cardiac pacemaking, particularly in association with Ca2+ release from the sarcoplasmic reticulum (SR) that occurs just before the action potential upstroke. The present experiments explore in more detail the contribution of NCX to...

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Autors principals: Sanders, L, Rakovic, S, Lowe, M, Mattick, P, Terrar, D
Format: Journal article
Idioma:English
Publicat: 2006