NEK1 kinase domain structure and its dynamic protein interactome after exposure to Cisplatin

NEK family kinases are serine/threonine kinases that have been functionally implicated in the regulation of the disjunction of the centrosome, the assembly of the mitotic spindle, the function of the primary cilium and the DNA damage response. NEK1 shows pleiotropic functions and has been found to b...

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Bibliographic Details
Main Authors: Melo-Hanchuk, T, Slepicka, P, Meirelles, G, Basei, F, Lovato, D, Granato, D, Pauletti, B, Domingues, R, Leme, A, Pelegrini, A, Lenz, G, Knapp, S, Elkins, J, Kobarg, J
Format: Journal article
Language:English
Published: Springer Nature 2017