NEK1 kinase domain structure and its dynamic protein interactome after exposure to Cisplatin
NEK family kinases are serine/threonine kinases that have been functionally implicated in the regulation of the disjunction of the centrosome, the assembly of the mitotic spindle, the function of the primary cilium and the DNA damage response. NEK1 shows pleiotropic functions and has been found to b...
Main Authors: | Melo-Hanchuk, T, Slepicka, P, Meirelles, G, Basei, F, Lovato, D, Granato, D, Pauletti, B, Domingues, R, Leme, A, Pelegrini, A, Lenz, G, Knapp, S, Elkins, J, Kobarg, J |
---|---|
Format: | Journal article |
Language: | English |
Published: |
Springer Nature
2017
|
Similar Items
-
The Mitochondrial Connection: The Nek Kinases’ New Functional Axis in Mitochondrial Homeostasis
by: Fernanda L. Basei, et al.
Published: (2024-03-01) -
Checking NEKs: Overcoming a Bottleneck in Human Diseases
by: Andressa Peres de Oliveira, et al.
Published: (2020-04-01) -
Structure and regulation of the human Nek2 centrosomal kinase.
by: Rellos, P, et al.
Published: (2007) -
The NIMA-family kinase, Nek1 affects the stability of centrosomes and ciliogenesis
by: Quarmby Lynne M, et al.
Published: (2008-06-01) -
NEK6 Regulates Redox Balance and DNA Damage Response in DU-145 Prostate Cancer Cells
by: Isadora Carolina Betim Pavan, et al.
Published: (2023-01-01)