The cholecystokinin receptor antagonist devazepide enhances morphine-induced analgesia but not morphine-induced respiratory depression in the squirrel monkey.

The effects of the cholecystokinin antagonist devazepide on analgesia and respiratory depression induced by morphine in squirrel monkeys were examined. Pain thresholds were determined using the tail withdrawal procedure, in which monkeys restrained in chairs kept their tails in cool (35 degrees C) w...

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Bibliographic Details
Main Authors: Dourish, C, O'Neill, M, Schaffer, L, Siegl, P, Iversen, S
Format: Journal article
Language:English
Published: 1990