The m.13051G>A mitochondrial DNA mutation results in variable neurology and activated mitophagy

The m.13051G>A mitochondrial DNA mutation results in variable neurology and activated mitophagy

<p>Maternally-inherited mitochondrial DNA (mtDNA) mutations cause symptoms of Leber’s hereditary optic neuropathy (LHON) in~ 1 in 30,000 individuals. Most of the affected individuals lack respiratory chain defects and there is no proven prophylactic treatment.</p> <p>We identified...

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Bibliographic Details
Main Authors: Poulton, J, Dombi, E, Diot, A, Morten, K, Carver, J, Lodge, T, Fratter, C, Ng, Y, Liao, C, Muir, R, Blakely, E, Hargreaves, I, Al-Dosary, M, Sarkar, G, Hickman, S, Downes, S, Jayawant, S, Yu-Wai-Man, P, Taylor, R
Format: Journal article
Published: American Association of Neurology 2016

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