Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

The analysis of proteome-wide phosphorylation events is still a major analytical challenge because of the enormous complexity of protein phosphorylation networks. In this work, we evaluate the complementarity of Lys-N, Lys-C, and trypsin with regard to their ability to contribute to the global analy...

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Bibliographic Details
Main Authors: Gauci, S, Helbig, A, Slijper, M, Krijgsveld, J, Heck, A, Mohammed, S
Format: Journal article
Language:English
Published: 2009