Susceptibility of feline immunodeficiency virus/human immunodeficiency virus type 1 reverse transcriptase chimeras to non-nucleoside RT inhibitors.

To map the determinants of the lack of susceptibility of feline immunodeficiency virus (FIV) reverse transcriptase (RT) to anti human immunodeficiency virus type 1 (HIV-1) non-nucleoside RT inhibitors (NNRTIs), a variety of chimeric HIV-1/FIV RTs were constructed. The majority of chimeric RTs had an...

Descripción completa

Detalles Bibliográficos
Autores principales: Auwerx, J, Esnouf, R, De Clercq, E, Balzarini, J
Formato: Journal article
Lenguaje:English
Publicado: 2004