DR5 knockout mice are compromised in radiation-induced apoptosis.

DR5 (also called TRAIL receptor 2 and KILLER) is an apoptosis-inducing membrane receptor for tumor necrosis factor-related apoptosis-inducing ligand (also called TRAIL and Apo2 ligand). DR5 is a transcriptional target of p53, and its overexpression induces cell death in vitro. However, the in vivo b...

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Bibliographic Details
Main Authors:	Finnberg, N, Gruber, J, Fei, P, Rudolph, D, Bric, A, Kim, S, Burns, T, Ajuha, H, Page, R, Wu, G, Chen, Y, Mckenna, W, Bernhard, E, Lowe, S, Mak, T, El-Deiry, W
Format:	Journal article
Language:	English
Published:	2005

DR5 knockout mice are compromised in radiation-induced apoptosis.

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