Safety and immunogenicity of heterologous prime-boost immunisation with Plasmodium falciparum malaria candidate vaccines, ChAd63 ME-TRAP and MVA ME-TRAP, in healthy Gambian and Kenyan adults.

BACKGROUND: Heterologous prime boost immunization with chimpanzee adenovirus 63 (ChAd63) and Modified vaccinia Virus Ankara (MVA) vectored vaccines is a strategy recently shown to be capable of inducing strong cell mediated responses against several antigens from the malaria parasite. ChAd63-MVA exp...

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Bibliographic Details
Main Authors: Ogwang, C, Afolabi, M, Kimani, D, Jagne, Y, Sheehy, S, Bliss, C, Duncan, C, Collins, K, Garcia Knight, M, Kimani, E, Anagnostou, N, Berrie, E, Moyle, S, Gilbert, S, Spencer, A, Soipei, P, Mueller, J, Okebe, J, Colloca, S, Cortese, R, Viebig, N, Roberts, R, Gantlett, K, Lawrie, A, Nicosia, A, Imoukhuede, E, Bejon, P, Urban, B, Flanagan, K, Ewer, K, Chilengi, R, Hill, A, Bojang, K
Format: Journal article
Language:English
Published: Public Library of Science 2013