Staurosporine enhances gonadotrophin-releasing hormone-stimulated luteinizing hormone secretion.
In intact sheep gonadotropes, the protein kinase inhibitor, staurosporine, inhibited the stimulatory effect of phorbol 12-myristate 13-acetate (PMA) on luteinizing hormone (LH) secretion. Under the same conditions staurosporine enhanced gonadotrophin-releasing hormone (GnRH)-stimulated LH exocytosis...
Main Authors: | , , , , |
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Format: | Journal article |
Language: | English |
Published: |
1990
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