Staurosporine enhances gonadotrophin-releasing hormone-stimulated luteinizing hormone secretion.

In intact sheep gonadotropes, the protein kinase inhibitor, staurosporine, inhibited the stimulatory effect of phorbol 12-myristate 13-acetate (PMA) on luteinizing hormone (LH) secretion. Under the same conditions staurosporine enhanced gonadotrophin-releasing hormone (GnRH)-stimulated LH exocytosis...

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Bibliographic Details
Main Authors: Van Der Merwe, P, Millar, R, Wakefield, I, Macrae, M, Davidson, J
Format: Journal article
Language:English
Published: 1990