Staurosporine enhances gonadotrophin-releasing hormone-stimulated luteinizing hormone secretion.
In intact sheep gonadotropes, the protein kinase inhibitor, staurosporine, inhibited the stimulatory effect of phorbol 12-myristate 13-acetate (PMA) on luteinizing hormone (LH) secretion. Under the same conditions staurosporine enhanced gonadotrophin-releasing hormone (GnRH)-stimulated LH exocytosis...
Main Authors: | Van Der Merwe, P, Millar, R, Wakefield, I, Macrae, M, Davidson, J |
---|---|
Format: | Journal article |
Language: | English |
Published: |
1990
|
Similar Items
-
Mechanisms of luteinizing hormone secretion: new insights from studies with permeabilized cells.
by: Davidson, J, et al.
Published: (1991) -
Mechanisms of luteinizing-hormone exocytosis in Staphylococcus aureus-alpha-toxin-permeabilized sheep gonadotropes.
by: Van Der Merwe, P, et al.
Published: (1989) -
Cyclic AMP stimulates luteinizing-hormone (lutropin) exocytosis in permeabilized sheep anterior-pituitary cells. Synergism with protein kinase C and calcium.
by: Macrae, M, et al.
Published: (1990) -
Calcium stimulates luteinizing-hormone (lutropin) exocytosis by a mechanism independent of protein kinase C.
by: Van Der Merwe, P, et al.
Published: (1990) -
Involvement of pertussis toxin-sensitive and -insensitive GTP-binding proteins in luteinizing hormone exocytosis distal to second messenger generation.
by: Davidson, J, et al.
Published: (1992)