Dose-finding study of the novel tuberculosis vaccine, MVA85A, in healthy BCG-vaccinated infants.

BACKGROUND: BCG, the only licensed tuberculosis vaccine, affords poor protection against lung tuberculosis in infants and children. A new tuberculosis vaccine, which may enhance the BCG-induced immune response, is urgently needed. We assessed the safety of and characterized the T cell response induc...

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Bibliographic Details
Main Authors: Scriba, T, Tameris, M, Mansoor, N, Smit, E, van der Merwe, L, Mauff, K, Hughes, E, Moyo, S, Brittain, N, Lawrie, A, Mulenga, H, de Kock, M, Gelderbloem, S, Veldsman, A, Hatherill, M, Geldenhuys, H, Hill, A, Hussey, G, Mahomed, H, Hanekom, W, Mcshane, H
Format: Journal article
Language:English
Published: 2011