Dose-finding study of the novel tuberculosis vaccine, MVA85A, in healthy BCG-vaccinated infants.

Dose-finding study of the novel tuberculosis vaccine, MVA85A, in healthy BCG-vaccinated infants.

BACKGROUND: BCG, the only licensed tuberculosis vaccine, affords poor protection against lung tuberculosis in infants and children. A new tuberculosis vaccine, which may enhance the BCG-induced immune response, is urgently needed. We assessed the safety of and characterized the T cell response induc...

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Autors principals: Scriba, T, Tameris, M, Mansoor, N, Smit, E, van der Merwe, L, Mauff, K, Hughes, E, Moyo, S, Brittain, N, Lawrie, A, Mulenga, H, de Kock, M, Gelderbloem, S, Veldsman, A, Hatherill, M, Geldenhuys, H, Hill, A, Hussey, G, Mahomed, H, Hanekom, W, Mcshane, H
Format: Journal article
Idioma:English
Publicat: 2011

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