The orexigenic effect of ghrelin is mediated through central activation of the endogenous cannabinoid system.

INTRODUCTION: Ghrelin and cannabinoids stimulate appetite, this effect possibly being mediated by the activation of hypothalamic AMP-activated protein kinase (AMPK), a key enzyme in appetite and metabolism regulation. The cannabinoid receptor type 1 (CB1) antagonist rimonabant can block the orexige...

詳細記述

書誌詳細
主要な著者: Kola, B, Farkas, I, Christ-Crain, M, Wittmann, G, Lolli, F, Amin, F, Harvey-White, J, Liposits, Z, Kunos, G, Grossman, AB, Fekete, C, Korbonits, M
フォーマット: Journal article
言語:English
出版事項: 2008