Laterally stabilized complexes of DNA with linear reducible polycations: strategy for triggered intracellular activation of DNA delivery vectors

Target-specific DNA delivery requires vectors that combine stability in the biological milieu, receptor-mediated uptake into target cells, and intracellular activation to mediate transgene expression. This is achieved here using polymer-coated vectors based on plasmid DNA complexed with a reductivel...

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Bibliographic Details
Main Authors: Oupický, D, Parker, AL, Seymour, LW
Format: Journal article
Language:English
Published: American Chemical Society 2001