Endocannabinoids control spasticity in a multiple sclerosis model.

Spasticity is a complicating sign in multiple sclerosis that also develops in a model of chronic relapsing experimental autoimmune encephalomyelitis (CREAE) in mice. In areas associated with nerve damage, increased levels of the endocannabinoids, anandamide (arachidonoylethanolamide, AEA) and 2-arac...

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Bibliographic Details
Main Authors: Baker, D, Pryce, G, Croxford, J, Brown, P, Pertwee, R, Makriyannis, A, Khanolkar, A, Layward, L, Fezza, F, Bisogno, T, Di Marzo, V
Format: Journal article
Language:English
Published: 2001