Neuropilin 1 and 2 control cranial gangliogenesis and axon guidance through neural crest cells.

Neuropilin (NRP) receptors and their class 3 semaphorin (SEMA3) ligands play well-established roles in axon guidance, with loss of NRP1, NRP2, SEMA3A or SEMA3F causing defasciculation and errors in growth cone guidance of peripherally projecting nerves. Here we report that loss of NRP1 or NRP2 also...

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Bibliographic Details
Main Authors: Schwarz, Q, Vieira, J, Howard, B, Eickholt, B, Ruhrberg, C
Format: Journal article
Language:English
Published: 2008