The IGF receptor as anticancer treatment target.
The type 1 insulin-like growth factor receptor (IGF-1R) is overexpressed by many tumours and mediates proliferation, motility and apoptosis protection. Tumour growth and metastasis can be blocked by agents that inhibit IGF-1R expression or function, suggesting the IGF-1R as a promising treatment tar...
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| Formaat: | Journal article |
| Taal: | English |
| Gepubliceerd in: |
2004
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