Changes in the cardiac metabolome caused by perhexiline treatment in a mouse model of hypertrophic cardiomyopathy.

Energy depletion has been highlighted as an important contributor to the pathology of hypertrophic cardiomyopathy (HCM), a common inherited cardiac disease. Pharmacological reversal of energy depletion appears an attractive approach and the use of perhexiline has been proposed as it is thought to sh...

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Bibliographic Details
Main Authors: Gehmlich, K, Dodd, M, William Allwood, J, Kelly, M, Bellahcene, M, Lad, H, Stockenhuber, A, Hooper, C, Ashrafian, H, Redwood, C, Carrier, L, Dunn, W
Format: Journal article
Language:English
Published: 2014