Impact of a single HLA-A*24:02-associated escape mutation on the detrimental effect of HLA-B*35:01 in HIV-1 control

<p>Background</p> <p>HLA-B*35 is an HLA allele associated with rapid progression to AIDS. However, a mechanism underlying the detrimental effect of HLA-B*35 on disease outcome remains unknown. Recent studies demonstrated that most prevalent subtype HLA-B*35:01 is a detrimental alle...

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Bibliographic Details
Main Authors: Murakoshi, H, Koyanagi, M, Akahoshi, T, Chikata, T, Kuse, N, Gatanaga, H, Rowland-Jones, S, Oka, S, Takiguchi, M
Format: Journal article
Language:English
Published: Elsevier 2018