Lipoproteins act as vehicles for lipid antigen delivery and activation of invariant natural killer T cells

Lipoproteins act as vehicles for lipid antigen delivery and activation of invariant natural killer T cells

Invariant natural killer T (iNKT) cells act at the interface between lipid metabolism and immunity because of their restriction to lipid antigens presented on CD1d by antigen-presenting cells (APCs). How foreign lipid antigens are delivered to APCs remains elusive. Since lipoproteins routinely bind...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoirí:	Engelen, SE, Ververs, FA, Markovska, A, Lagerholm, BC, Kraaijenhof, JM, Yousif, LI, Zurke, Y-X, Gulersonmez, CM, Kooijman, S, Goddard, M, van Eijkeren, RJ, Jervis, PJ, Besra, GS, Haitjema, S, Asselbergs, FW, Kalkhoven, E, Ploegh, HL, Boes, M, Cerundolo, V, Hovingh, GK, Salio, M, Stigter, EC, Rensen, PC, Monaco, C, Schipper, HS
Formáid:	Journal article
Teanga:	English
Foilsithe / Cruthaithe:	American Society for Clinical Investigation 2023

Míreanna comhchosúla

Lipoproteins act as vehicles for lipid antigen delivery and activation of invariant natural killer T cells
de réir: Suzanne E. Engelen, et al.
Foilsithe / Cruthaithe: (2023-05-01)

Synthesis of truncated analogues of the iNKT cell agonist, α-galactosyl ceramide (KRN7000), and their biological evaluation
de réir: Veerapen, N, et al.
Foilsithe / Cruthaithe: (2011)

Synthesis of truncated analogues of the iNKT cell agonist, α-galactosyl ceramide (KRN7000), and their biological evaluation.
de réir: Veerapen, N, et al.
Foilsithe / Cruthaithe: (2011)

Immunometabolic factors in adolescent chronic disease are associated with Th1 skewing of invariant Natural Killer T cells
de réir: Ververs, FA, et al.
Foilsithe / Cruthaithe: (2021)

Towards multivalent CD1d ligands: Synthesis and biological activity of homodimeric α-galactosyl ceramide analogues
de réir: Jervis, P, et al.
Foilsithe / Cruthaithe: (2012)

Towards multivalent CD1d ligands: synthesis and biological activity of homodimeric α-galactosyl ceramide analogues.
de réir: Jervis, P, et al.
Foilsithe / Cruthaithe: (2012)

Therapeutic strategies targeting inflammation and immunity in atherosclerosis: how to proceed?
de réir: Engelen, SE, et al.
Foilsithe / Cruthaithe: (2022)

Invariant NKT Cell at the Interface between Innate and Adaptive Immunity
de réir: Salio, M, et al.
Foilsithe / Cruthaithe: (2011)

Linking inflammation to natural killer T cell activation
de réir: Salio, M, et al.
Foilsithe / Cruthaithe: (2009)

Harnessing NKT cells for therapeutic applications.
de réir: Cerundolo, V, et al.
Foilsithe / Cruthaithe: (2007)

Viral immunity: cross-priming with the help of TLR3.
de réir: Salio, M, et al.
Foilsithe / Cruthaithe: (2005)

Proteomic Signatures of Genetically Predicted and Pharmacologically Observed PCSK9 Inhibition
de réir: Jordan M. Kraaijenhof, et al.
Foilsithe / Cruthaithe: (2024-06-01)

Targeted inhibition of glycogen synthase kinase-3 using 9-ING-41 (elraglusib) enhances CD8 T-cell-reactivity against neuroblastoma cells
de réir: A. Markovska, et al.
Foilsithe / Cruthaithe: (2024-09-01)

Impaired selection of invariant natural killer T cells in diverse mouse models of glycosphingolipid lysosomal storage diseases.
de réir: Gadola, S, et al.
Foilsithe / Cruthaithe: (2006)

Modulation of human natural killer T cell ligands on TLR-mediated antigen-presenting cell activation.
de réir: Salio, M, et al.
Foilsithe / Cruthaithe: (2007)

The year in cardiovascular medicine 2020: digital health and innovation [Год в сердечно-сосудистой медицине, 2020 г.: цифровое здравоохранение и инновации]
de réir: Antoniades, C, et al.
Foilsithe / Cruthaithe: (2021)

Harnessing the power of invariant natural killer T cells in cancer immunotherapy
de réir: Bedard, M, et al.
Foilsithe / Cruthaithe: (2017)

The immune modulating properties of mucosal-associated invariant T cells
de réir: Ioannidis, M, et al.
Foilsithe / Cruthaithe: (2020)

Dendritic cell maturation is induced by mycoplasma infection but not by necrotic cells.
de réir: Salio, M, et al.
Foilsithe / Cruthaithe: (2000)

T cell receptors get back to basics.
de réir: Jones, E, et al.
Foilsithe / Cruthaithe: (2007)

Dendritic cells: a journey from laboratory to clinic.
de réir: Cerundolo, V, et al.
Foilsithe / Cruthaithe: (2004)

Recent advances in processing and presentation of CD1 bound lipid antigens.
de réir: Salio, M, et al.
Foilsithe / Cruthaithe: (2010)

Design, synthesis, and functional activity of labeled CD1d glycolipid agonists.
de réir: Jervis, P, et al.
Foilsithe / Cruthaithe: (2013)

A single-cell genomic based investigation of immune cells in the aorta and adipose tissue during metabolic disease progression
de réir: Zurke, YX
Foilsithe / Cruthaithe: (2023)

B cell receptor-mediated uptake of CD1d-restricted antigen augments antibody responses by recruiting invariant NKT cell help in vivo.
de réir: Barral, P, et al.
Foilsithe / Cruthaithe: (2008)

Harnessing invariant NKT cells in vaccination strategies.
de réir: Cerundolo, V, et al.
Foilsithe / Cruthaithe: (2009)

Valpha24-JalphaQ-independent, CD1d-restricted recognition of alpha-galactosylceramide by human CD4(+) and CD8alphabeta(+) T lymphocytes.
de réir: Gadola, S, et al.
Foilsithe / Cruthaithe: (2002)

Potential role for CD1d restricted T-cells in the immunopathology of sarcoidosis
de réir: Ho, L, et al.
Foilsithe / Cruthaithe: (2003)

Essential role for autophagy during invariant NKT cell development
de réir: Salio, M, et al.
Foilsithe / Cruthaithe: (2014)

Lipid-modifying agents, from statins to PCSK9 inhibitors: JACC focus seminar
de réir: Preiss, D, et al.
Foilsithe / Cruthaithe: (2020)

Immunotherapy of colorectal cancer.
de réir: Smith, C, et al.
Foilsithe / Cruthaithe: (2002)

A closer look at CD1d molecules: new horizons in studying NKT cells.
de réir: Stronge, V, et al.
Foilsithe / Cruthaithe: (2007)

The use of HLA class I tetramers to design a vaccination strategy for melanoma patients.
de réir: Palmowski, M, et al.
Foilsithe / Cruthaithe: (2002)

Biology of CD1- and MR1-restricted T cells.
de réir: Salio, M, et al.
Foilsithe / Cruthaithe: (2014)

Genetic analysis of emerging risk factors in coronary artery disease
de réir: van Iperen, E, et al.
Foilsithe / Cruthaithe: (2016)

Low‐Density Lipoprotein Cholesterol Attributable Cardiovascular Disease Risk Is Sex Specific
de réir: Arjen J. Cupido, et al.
Foilsithe / Cruthaithe: (2022-06-01)

Expression of MHC class I-related Chain B (MICB) molecules on renal transplant biopsies.
de réir: Quiroga, I, et al.
Foilsithe / Cruthaithe: (2006)

Lack of dendritic cell maturation by the plant toxin ricin.
de réir: Smith, D, et al.
Foilsithe / Cruthaithe: (2004)

Cerundolo et al. respond
de réir: De Santo, C, et al.
Foilsithe / Cruthaithe: (2011)

Structural and functional aspects of lipid binding by CD1 molecules.
de réir: Silk, J, et al.
Foilsithe / Cruthaithe: (2008)