Lipoproteins act as vehicles for lipid antigen delivery and activation of invariant natural killer T cells

Lipoproteins act as vehicles for lipid antigen delivery and activation of invariant natural killer T cells

Invariant natural killer T (iNKT) cells act at the interface between lipid metabolism and immunity because of their restriction to lipid antigens presented on CD1d by antigen-presenting cells (APCs). How foreign lipid antigens are delivered to APCs remains elusive. Since lipoproteins routinely bind...

Полное описание

Библиографические подробности
Главные авторы:	Engelen, SE, Ververs, FA, Markovska, A, Lagerholm, BC, Kraaijenhof, JM, Yousif, LI, Zurke, Y-X, Gulersonmez, CM, Kooijman, S, Goddard, M, van Eijkeren, RJ, Jervis, PJ, Besra, GS, Haitjema, S, Asselbergs, FW, Kalkhoven, E, Ploegh, HL, Boes, M, Cerundolo, V, Hovingh, GK, Salio, M, Stigter, EC, Rensen, PC, Monaco, C, Schipper, HS
Формат:	Journal article
Язык:	English
Опубликовано:	American Society for Clinical Investigation 2023

Схожие документы

Lipoproteins act as vehicles for lipid antigen delivery and activation of invariant natural killer T cells
по: Suzanne E. Engelen, и др.
Опубликовано: (2023-05-01)

Cytokine Output of Adipocyte-iNKT Cell Interplay Is Skewed by a Lipid-Rich Microenvironment
по: Robert J. van Eijkeren, и др.
Опубликовано: (2020-07-01)

Synthesis of truncated analogues of the iNKT cell agonist, α-galactosyl ceramide (KRN7000), and their biological evaluation
по: Veerapen, N, и др.
Опубликовано: (2011)

Synthesis of truncated analogues of the iNKT cell agonist, α-galactosyl ceramide (KRN7000), and their biological evaluation.
по: Veerapen, N, и др.
Опубликовано: (2011)

Immunometabolic factors in adolescent chronic disease are associated with Th1 skewing of invariant Natural Killer T cells
по: Ververs, FA, и др.
Опубликовано: (2021)

Towards multivalent CD1d ligands: Synthesis and biological activity of homodimeric α-galactosyl ceramide analogues
по: Jervis, P, и др.
Опубликовано: (2012)

Towards multivalent CD1d ligands: synthesis and biological activity of homodimeric α-galactosyl ceramide analogues.
по: Jervis, P, и др.
Опубликовано: (2012)

Therapeutic strategies targeting inflammation and immunity in atherosclerosis: how to proceed?
по: Engelen, SE, и др.
Опубликовано: (2022)

Immunometabolic factors in adolescent chronic disease are associated with Th1 skewing of invariant Natural Killer T cells
по: Francesca A. Ververs, и др.
Опубликовано: (2021-10-01)

Invariant NKT Cell at the Interface between Innate and Adaptive Immunity
по: Salio, M, и др.
Опубликовано: (2011)

Linking inflammation to natural killer T cell activation
по: Salio, M, и др.
Опубликовано: (2009)

Harnessing NKT cells for therapeutic applications.
по: Cerundolo, V, и др.
Опубликовано: (2007)

Viral immunity: cross-priming with the help of TLR3.
по: Salio, M, и др.
Опубликовано: (2005)

Linking inflammation to natural killer T cell activation.
по: Mariolina Salio, и др.
Опубликовано: (2009-10-01)

Proteomic Signatures of Genetically Predicted and Pharmacologically Observed PCSK9 Inhibition
по: Jordan M. Kraaijenhof, и др.
Опубликовано: (2024-06-01)

Targeted inhibition of glycogen synthase kinase-3 using 9-ING-41 (elraglusib) enhances CD8 T-cell-reactivity against neuroblastoma cells
по: A. Markovska, и др.
Опубликовано: (2024-09-01)

Impaired selection of invariant natural killer T cells in diverse mouse models of glycosphingolipid lysosomal storage diseases.
по: Gadola, S, и др.
Опубликовано: (2006)

Modulation of human natural killer T cell ligands on TLR-mediated antigen-presenting cell activation.
по: Salio, M, и др.
Опубликовано: (2007)

Harnessing the power of invariant natural killer T cells in cancer immunotherapy
по: Bedard, M, и др.
Опубликовано: (2017)

The immune modulating properties of mucosal-associated invariant T cells
по: Ioannidis, M, и др.
Опубликовано: (2020)

Dendritic cell maturation is induced by mycoplasma infection but not by necrotic cells.
по: Salio, M, и др.
Опубликовано: (2000)

T cell receptors get back to basics.
по: Jones, E, и др.
Опубликовано: (2007)

Dendritic cells: a journey from laboratory to clinic.
по: Cerundolo, V, и др.
Опубликовано: (2004)

Recent advances in processing and presentation of CD1 bound lipid antigens.
по: Salio, M, и др.
Опубликовано: (2010)

The Immune Modulating Properties of Mucosal-Associated Invariant T Cells
по: Melina Ioannidis, и др.
Опубликовано: (2020-08-01)

Harnessing the Power of Invariant Natural Killer T Cells in Cancer Immunotherapy
по: Melissa Bedard, и др.
Опубликовано: (2017-12-01)

A single-cell genomic based investigation of immune cells in the aorta and adipose tissue during metabolic disease progression
по: Zurke, YX
Опубликовано: (2023)

Design, synthesis, and functional activity of labeled CD1d glycolipid agonists.
по: Jervis, P, и др.
Опубликовано: (2013)

The year in cardiovascular medicine 2020: digital health and innovation [Год в сердечно-сосудистой медицине, 2020 г.: цифровое здравоохранение и инновации]
по: Antoniades, C, и др.
Опубликовано: (2021)

Harnessing invariant NKT cells in vaccination strategies.
по: Cerundolo, V, и др.
Опубликовано: (2009)

Valpha24-JalphaQ-independent, CD1d-restricted recognition of alpha-galactosylceramide by human CD4(+) and CD8alphabeta(+) T lymphocytes.
по: Gadola, S, и др.
Опубликовано: (2002)

B cell receptor-mediated uptake of CD1d-restricted antigen augments antibody responses by recruiting invariant NKT cell help in vivo.
по: Barral, P, и др.
Опубликовано: (2008)

Essential role for autophagy during invariant NKT cell development
по: Salio, M, и др.
Опубликовано: (2014)

Potential role for CD1d restricted T-cells in the immunopathology of sarcoidosis
по: Ho, L, и др.
Опубликовано: (2003)

Immunotherapy of colorectal cancer.
по: Smith, C, и др.
Опубликовано: (2002)

A closer look at CD1d molecules: new horizons in studying NKT cells.
по: Stronge, V, и др.
Опубликовано: (2007)

The use of HLA class I tetramers to design a vaccination strategy for melanoma patients.
по: Palmowski, M, и др.
Опубликовано: (2002)

Biology of CD1- and MR1-restricted T cells.
по: Salio, M, и др.
Опубликовано: (2014)

Lipid-modifying agents, from statins to PCSK9 inhibitors: JACC focus seminar
по: Preiss, D, и др.
Опубликовано: (2020)

Expression of MHC class I-related Chain B (MICB) molecules on renal transplant biopsies.
по: Quiroga, I, и др.
Опубликовано: (2006)