Tissue expression and functional insights into HIF prolyl hydroxylase domain enzymes

<p>This research programme investigated the expression of prolyl hydroxylase (PHD) proteins in rodent tissues. The importance of PHD enzymes lies in their ability to render oxygen sensitivity to Hypoxia inducible factor (HIF), the principal mediator of intracellular oxygen homeostasis. The fir...

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Bibliographic Details
Main Author: Wijeyekoon, JB
Other Authors: Pugh, C
Format: Thesis
Language:English
Published: 2013
Subjects: