Tissue expression and functional insights into HIF prolyl hydroxylase domain enzymes

Tissue expression and functional insights into HIF prolyl hydroxylase domain enzymes

<p>This research programme investigated the expression of prolyl hydroxylase (PHD) proteins in rodent tissues. The importance of PHD enzymes lies in their ability to render oxygen sensitivity to Hypoxia inducible factor (HIF), the principal mediator of intracellular oxygen homeostasis. The fir...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолч:	Wijeyekoon, JB
Бусад зохиолчид:	Pugh, C
Формат:	Дипломын ажил
Хэл сонгох:	English
Хэвлэсэн:	2013
Нөхцлүүд:	Medical Sciences Clinical laboratory sciences

Ижил төстэй зүйлс

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-н: Stolze, I, зэрэг
Хэвлэсэн: (2006)

Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases
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Хэвлэсэн: (2016)

Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases
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Хэвлэсэн: (2016-08-01)

Tolerance in renal transplantation: is mixed chimerism the missing link?
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Хэвлэсэн: (2009)

The use of dioxygen by HIF prolyl hydroxylase (PHD1).
-н: McNeill, L, зэрэг
Хэвлэсэн: (2002)

Determination and comparison of specific activity of the HIF-prolyl hydroxylases.
-н: Tuckerman, JR, зэрэг
Хэвлэсэн: (2004)

2-oxoglutarate analogue inhibitors of HIF prolyl hydroxylase.
-н: Mole, D, зэрэг
Хэвлэсэн: (2003)

Analogues of dealanylalahopcin are inhibitors of human HIF prolyl hydroxylases.
-н: Schlemminger, I, зэрэг
Хэвлэсэн: (2003)

Studies on HIF hydroxylases
-н: Webb, J
Хэвлэсэн: (2008)

Cortical dynamics subserving visual apparent motion
-н: Ahmed, B, зэрэг
Хэвлэсэн: (2008)

Inhibition of HIF-prolyl hydroxylases improves healing of intestinal anastomoses
-н: Moritz J. Strowitzki, зэрэг
Хэвлэсэн: (2021-04-01)

Structure–activity relationship and crystallographic studies on 4-hydroxypyrimidine HIF prolyl hydroxylase domain inhibitors
-н: Holt-Martyn, JP, зэрэг
Хэвлэсэн: (2019)

Lack of activity of recombinant HIF prolyl hydroxylases (PHDs) on reported non-HIF substrates
-н: Cockman, M, зэрэг
Хэвлэсэн: (2019)

Lack of activity of recombinant HIF prolyl hydroxylases (PHDs) on reported non-HIF substrates
-н: Matthew E Cockman, зэрэг
Хэвлэсэн: (2019-09-01)

Prolyl hydroxylase domain enzyme PHD2 inhibits proliferation and metabolism in non-small cell lung cancer cells in HIF-dependent and HIF-independent manners
-н: Hongyan Deng, зэрэг
Хэвлэсэн: (2024-06-01)

The role of CCL25 and CCR9 in intestinal inflammation
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Хэвлэсэн: (2013)

Adaptive changes of influenza virus A/H5N1 neuraminidase in vitro and in vivo
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Хэвлэсэн: (2014)

Angiogenesis in human lung tumours
-н: Ferguson, ML
Хэвлэсэн: (2008)

Editorial commentary: Understanding BCG is the key to improving it
-н: McShane, H
Хэвлэсэн: (2014)

Human T-lymphotropic virus type 1(HTLV-1) associated infective dermatitis
-н: Hlela, C
Хэвлэсэн: (2011)

Tuning the transcriptional response to hypoxia by inhibiting HIF prolyl- and asparaginyl-hydroxylases
-н: Chan, M, зэрэг
Хэвлэсэн: (2016)

Molecular and Cellular Mechanisms of HIF Prolyl Hydroxylase inhibitors in Clinical Trials
-н: Yeh, TL, зэрэг
Хэвлэсэн: (2017)

Neuroprotective Effect of HIF Prolyl Hydroxylase Inhibition in an In Vitro Hypoxia Model
-н: Maria Savyuk, зэрэг
Хэвлэсэн: (2020-07-01)

HIF Prolyl Hydroxylase Inhibitors for COVID-19 Treatment: Pros and Cons
-н: Andrey A. Poloznikov, зэрэг
Хэвлэсэн: (2021-01-01)

Novel and selective small molecule inhibitors and activators for the prolyl hydroxylase domain enzyme
-н: Holt-Martyn, J
Хэвлэсэн: (2018)

Investigating the dependence of the hypoxia-inducible factor hydroxylases (factor inhibiting HIF and prolyl hydroxylase domain 2) on ascorbate and other reducing agents.
-н: Flashman, E, зэрэг
Хэвлэсэн: (2010)

Probing the molecular basis of melanopsin induced light sensitivity
-н: Vachtsevanos, AN
Хэвлэсэн: (2012)

Therapeutic Effect of Extracellular Vesicles Derived from HIF Prolyl Hydroxylase Domain Enzyme Inhibitor-Treated Cells on Renal Ischemia/Reperfusion Injury
-н: Zhao-Ying Ding, зэрэг
Хэвлэсэн: (2022-03-01)

HR23B, a biomarker for HDAC inhibitors
-н: Khan, OA
Хэвлэсэн: (2013)

Risk factors for haemorrhage in patients with haematological malignancies
-н: Estcourt, LJ
Хэвлэсэн: (2014)

Transcription regulation of Nrp1 during endothelial cell differentiation
-н: Zhao, Z
Хэвлэсэн: (2014)

Selective small molecule probes for the hypoxia inducible factor (HIF) prolyl hydroxylases.
-н: Chowdhury, R, зэрэг
Хэвлэсэн: (2013)

Structural, biochemical and inhibition studies on hypoxia-inducible factor (HIF) prolyl hydroxylases
-н: Lippl, K
Хэвлэсэн: (2018)

HIF prolyl and asparaginyl hydroxylases in the biological response to intracellular O(2) levels.
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Хэвлэсэн: (2003)

Impact of HIF prolyl hydroxylase inhibitors in heart failure patients with renal anemia
-н: Takahiro Kambara, зэрэг
Хэвлэсэн: (2024-03-01)

HIF-α Prolyl Hydroxylase Inhibitors and Their Implications for Biomedicine: A Comprehensive Review
-н: Kiichi Hirota
Хэвлэсэн: (2021-04-01)

The HIF-prolyl hydroxylases have distinct and nonredundant roles in colitis-associated cancer
-н: Kilian B. Kennel, зэрэг
Хэвлэсэн: (2022-11-01)

Network activity in primary hippocampal cultures upon HIF-prolyl hydroxylase inhibition
-н: Savyuk, Maria Olegovna, зэрэг
Хэвлэсэн: (2021-05-01)

Evaluation of strain circulation and the epidemiology of enteric fever caused
-н: Karkey, A, зэрэг
Хэвлэсэн: (2012)

International best practice: Understanding the core difference between medical laboratory science and clinical laboratory medicine in Nigeria
-н: Felix Archibong, зэрэг
Хэвлэсэн: (2021-01-01)