Tissue expression and functional insights into HIF prolyl hydroxylase domain enzymes

Tissue expression and functional insights into HIF prolyl hydroxylase domain enzymes

<p>This research programme investigated the expression of prolyl hydroxylase (PHD) proteins in rodent tissues. The importance of PHD enzymes lies in their ability to render oxygen sensitivity to Hypoxia inducible factor (HIF), the principal mediator of intracellular oxygen homeostasis. The fir...

Bibliográfalaš dieđut
Váldodahkki:	Wijeyekoon, JB
Eará dahkkit:	Pugh, C
Materiálatiipa:	Oahppočájánas
Giella:	English
Almmustuhtton:	2013
Fáttát:	Medical Sciences Clinical laboratory sciences

Geahča maid

Regulation of HIF: prolyl hydroxylases.
Dahkki: Stolze, I, et al.
Almmustuhtton: (2006)

Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases
Dahkki: Chowdhury, R, et al.
Almmustuhtton: (2016)

Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases
Dahkki: Rasheduzzaman Chowdhury, et al.
Almmustuhtton: (2016-08-01)

Tolerance in renal transplantation: is mixed chimerism the missing link?
Dahkki: Janes, S, et al.
Almmustuhtton: (2009)

The use of dioxygen by HIF prolyl hydroxylase (PHD1).
Dahkki: McNeill, L, et al.
Almmustuhtton: (2002)

Determination and comparison of specific activity of the HIF-prolyl hydroxylases.
Dahkki: Tuckerman, JR, et al.
Almmustuhtton: (2004)

2-oxoglutarate analogue inhibitors of HIF prolyl hydroxylase.
Dahkki: Mole, D, et al.
Almmustuhtton: (2003)

Analogues of dealanylalahopcin are inhibitors of human HIF prolyl hydroxylases.
Dahkki: Schlemminger, I, et al.
Almmustuhtton: (2003)

Studies on HIF hydroxylases
Dahkki: Webb, J
Almmustuhtton: (2008)

Cortical dynamics subserving visual apparent motion
Dahkki: Ahmed, B, et al.
Almmustuhtton: (2008)

Inhibition of HIF-prolyl hydroxylases improves healing of intestinal anastomoses
Dahkki: Moritz J. Strowitzki, et al.
Almmustuhtton: (2021-04-01)

Structure–activity relationship and crystallographic studies on 4-hydroxypyrimidine HIF prolyl hydroxylase domain inhibitors
Dahkki: Holt-Martyn, JP, et al.
Almmustuhtton: (2019)

Lack of activity of recombinant HIF prolyl hydroxylases (PHDs) on reported non-HIF substrates
Dahkki: Cockman, M, et al.
Almmustuhtton: (2019)

Lack of activity of recombinant HIF prolyl hydroxylases (PHDs) on reported non-HIF substrates
Dahkki: Matthew E Cockman, et al.
Almmustuhtton: (2019-09-01)

Prolyl hydroxylase domain enzyme PHD2 inhibits proliferation and metabolism in non-small cell lung cancer cells in HIF-dependent and HIF-independent manners
Dahkki: Hongyan Deng, et al.
Almmustuhtton: (2024-06-01)

The role of CCL25 and CCR9 in intestinal inflammation
Dahkki: Wendt, E, et al.
Almmustuhtton: (2013)

Adaptive changes of influenza virus A/H5N1 neuraminidase in vitro and in vivo
Dahkki: Le Nguyen, T
Almmustuhtton: (2014)

Angiogenesis in human lung tumours
Dahkki: Ferguson, ML
Almmustuhtton: (2008)

Editorial commentary: Understanding BCG is the key to improving it
Dahkki: McShane, H
Almmustuhtton: (2014)

Human T-lymphotropic virus type 1(HTLV-1) associated infective dermatitis
Dahkki: Hlela, C
Almmustuhtton: (2011)

Tuning the transcriptional response to hypoxia by inhibiting HIF prolyl- and asparaginyl-hydroxylases
Dahkki: Chan, M, et al.
Almmustuhtton: (2016)

Molecular and Cellular Mechanisms of HIF Prolyl Hydroxylase inhibitors in Clinical Trials
Dahkki: Yeh, TL, et al.
Almmustuhtton: (2017)

Neuroprotective Effect of HIF Prolyl Hydroxylase Inhibition in an In Vitro Hypoxia Model
Dahkki: Maria Savyuk, et al.
Almmustuhtton: (2020-07-01)

HIF Prolyl Hydroxylase Inhibitors for COVID-19 Treatment: Pros and Cons
Dahkki: Andrey A. Poloznikov, et al.
Almmustuhtton: (2021-01-01)

Novel and selective small molecule inhibitors and activators for the prolyl hydroxylase domain enzyme
Dahkki: Holt-Martyn, J
Almmustuhtton: (2018)

Investigating the dependence of the hypoxia-inducible factor hydroxylases (factor inhibiting HIF and prolyl hydroxylase domain 2) on ascorbate and other reducing agents.
Dahkki: Flashman, E, et al.
Almmustuhtton: (2010)

Probing the molecular basis of melanopsin induced light sensitivity
Dahkki: Vachtsevanos, AN
Almmustuhtton: (2012)

Therapeutic Effect of Extracellular Vesicles Derived from HIF Prolyl Hydroxylase Domain Enzyme Inhibitor-Treated Cells on Renal Ischemia/Reperfusion Injury
Dahkki: Zhao-Ying Ding, et al.
Almmustuhtton: (2022-03-01)

HR23B, a biomarker for HDAC inhibitors
Dahkki: Khan, OA
Almmustuhtton: (2013)

Risk factors for haemorrhage in patients with haematological malignancies
Dahkki: Estcourt, LJ
Almmustuhtton: (2014)

Transcription regulation of Nrp1 during endothelial cell differentiation
Dahkki: Zhao, Z
Almmustuhtton: (2014)

Selective small molecule probes for the hypoxia inducible factor (HIF) prolyl hydroxylases.
Dahkki: Chowdhury, R, et al.
Almmustuhtton: (2013)

Structural, biochemical and inhibition studies on hypoxia-inducible factor (HIF) prolyl hydroxylases
Dahkki: Lippl, K
Almmustuhtton: (2018)

HIF prolyl and asparaginyl hydroxylases in the biological response to intracellular O(2) levels.
Dahkki: Masson, N, et al.
Almmustuhtton: (2003)

Impact of HIF prolyl hydroxylase inhibitors in heart failure patients with renal anemia
Dahkki: Takahiro Kambara, et al.
Almmustuhtton: (2024-03-01)

HIF-α Prolyl Hydroxylase Inhibitors and Their Implications for Biomedicine: A Comprehensive Review
Dahkki: Kiichi Hirota
Almmustuhtton: (2021-04-01)

The HIF-prolyl hydroxylases have distinct and nonredundant roles in colitis-associated cancer
Dahkki: Kilian B. Kennel, et al.
Almmustuhtton: (2022-11-01)

Network activity in primary hippocampal cultures upon HIF-prolyl hydroxylase inhibition
Dahkki: Savyuk, Maria Olegovna, et al.
Almmustuhtton: (2021-05-01)

Evaluation of strain circulation and the epidemiology of enteric fever caused
Dahkki: Karkey, A, et al.
Almmustuhtton: (2012)

International best practice: Understanding the core difference between medical laboratory science and clinical laboratory medicine in Nigeria
Dahkki: Felix Archibong, et al.
Almmustuhtton: (2021-01-01)