Tissue expression and functional insights into HIF prolyl hydroxylase domain enzymes

Tissue expression and functional insights into HIF prolyl hydroxylase domain enzymes

<p>This research programme investigated the expression of prolyl hydroxylase (PHD) proteins in rodent tissues. The importance of PHD enzymes lies in their ability to render oxygen sensitivity to Hypoxia inducible factor (HIF), the principal mediator of intracellular oxygen homeostasis. The fir...

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Chi tiết về thư mục
Tác giả chính:	Wijeyekoon, JB
Tác giả khác:	Pugh, C
Định dạng:	Luận văn
Ngôn ngữ:	English
Được phát hành:	2013
Những chủ đề:	Medical Sciences Clinical laboratory sciences

Những quyển sách tương tự

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Được phát hành: (2006)

Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases
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Được phát hành: (2016)

The use of dioxygen by HIF prolyl hydroxylase (PHD1).
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Được phát hành: (2002)

Determination and comparison of specific activity of the HIF-prolyl hydroxylases.
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Được phát hành: (2004)

2-oxoglutarate analogue inhibitors of HIF prolyl hydroxylase.
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Được phát hành: (2003)

Analogues of dealanylalahopcin are inhibitors of human HIF prolyl hydroxylases.
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Được phát hành: (2003)

Tolerance in renal transplantation: is mixed chimerism the missing link?
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Được phát hành: (2009)

Studies on HIF hydroxylases
Bằng: Webb, J
Được phát hành: (2008)

Structure–activity relationship and crystallographic studies on 4-hydroxypyrimidine HIF prolyl hydroxylase domain inhibitors
Bằng: Holt-Martyn, JP, et al.
Được phát hành: (2019)

Lack of activity of recombinant HIF prolyl hydroxylases (PHDs) on reported non-HIF substrates
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Được phát hành: (2019)

Lack of activity of recombinant HIF prolyl hydroxylases (PHDs) on reported non-HIF substrates
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Được phát hành: (2019-09-01)

Cortical dynamics subserving visual apparent motion
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Được phát hành: (2008)

Prolyl hydroxylase domain enzyme PHD2 inhibits proliferation and metabolism in non-small cell lung cancer cells in HIF-dependent and HIF-independent manners
Bằng: Hongyan Deng, et al.
Được phát hành: (2024-06-01)

Tuning the transcriptional response to hypoxia by inhibiting HIF prolyl- and asparaginyl-hydroxylases
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Được phát hành: (2016)

Molecular and Cellular Mechanisms of HIF Prolyl Hydroxylase inhibitors in Clinical Trials
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Được phát hành: (2017)

Neuroprotective Effect of HIF Prolyl Hydroxylase Inhibition in an In Vitro Hypoxia Model
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Được phát hành: (2020-07-01)

HIF Prolyl Hydroxylase Inhibitors for COVID-19 Treatment: Pros and Cons
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Được phát hành: (2021-01-01)

Novel and selective small molecule inhibitors and activators for the prolyl hydroxylase domain enzyme
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Được phát hành: (2018)

Investigating the dependence of the hypoxia-inducible factor hydroxylases (factor inhibiting HIF and prolyl hydroxylase domain 2) on ascorbate and other reducing agents.
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Được phát hành: (2010)

The role of CCL25 and CCR9 in intestinal inflammation
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Được phát hành: (2013)

Adaptive changes of influenza virus A/H5N1 neuraminidase in vitro and in vivo
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Được phát hành: (2014)

Angiogenesis in human lung tumours
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Được phát hành: (2008)

Editorial commentary: Understanding BCG is the key to improving it
Bằng: McShane, H
Được phát hành: (2014)

Human T-lymphotropic virus type 1(HTLV-1) associated infective dermatitis
Bằng: Hlela, C
Được phát hành: (2011)

Therapeutic Effect of Extracellular Vesicles Derived from HIF Prolyl Hydroxylase Domain Enzyme Inhibitor-Treated Cells on Renal Ischemia/Reperfusion Injury
Bằng: Zhao-Ying Ding, et al.
Được phát hành: (2022-03-01)

Selective small molecule probes for the hypoxia inducible factor (HIF) prolyl hydroxylases.
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Được phát hành: (2013)

Structural, biochemical and inhibition studies on hypoxia-inducible factor (HIF) prolyl hydroxylases
Bằng: Lippl, K
Được phát hành: (2018)

HIF prolyl and asparaginyl hydroxylases in the biological response to intracellular O(2) levels.
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Được phát hành: (2003)

Impact of HIF prolyl hydroxylase inhibitors in heart failure patients with renal anemia
Bằng: Takahiro Kambara, et al.
Được phát hành: (2024-03-01)

HIF-α Prolyl Hydroxylase Inhibitors and Their Implications for Biomedicine: A Comprehensive Review
Bằng: Kiichi Hirota
Được phát hành: (2021-04-01)

The HIF-prolyl hydroxylases have distinct and nonredundant roles in colitis-associated cancer
Bằng: Kilian B. Kennel, et al.
Được phát hành: (2022-11-01)

Probing the molecular basis of melanopsin induced light sensitivity
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Được phát hành: (2012)

HIF prolyl hydroxylases in the rat; organ distribution and changes in expression following hypoxia and coronary artery ligation.
Bằng: Willam, C, et al.
Được phát hành: (2006)

Mechanistic studies on human prolyl hydroxylase domain 2
Bằng: Fiorini, G
Được phát hành: (2024)

Structural basis of prolyl hydroxylase domain inhibition by Molidustat
Bằng: Figg, WD, et al.
Được phát hành: (2021)

Role of prolyl hydroxylase domain proteins in bone metabolism
Bằng: David Wolf, et al.
Được phát hành: (2022-03-01)

Prolyl hydroxylases and therapeutics.
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Được phát hành: (2010)

HR23B, a biomarker for HDAC inhibitors
Bằng: Khan, OA
Được phát hành: (2013)

Risk factors for haemorrhage in patients with haematological malignancies
Bằng: Estcourt, LJ
Được phát hành: (2014)

Transcription regulation of Nrp1 during endothelial cell differentiation
Bằng: Zhao, Z
Được phát hành: (2014)