Multi-stage models for the failure of complex systems, cascading disasters, and the onset of disease
Complex systems can fail through different routes, often progressing through a series of (rate-limiting) steps and modified by environmental exposures. The onset of disease, cancer in particular, is no different. Multi-stage models provide a simple but very general mathematical framework for studyin...
Main Author: | |
---|---|
Format: | Journal article |
Published: |
Public Library of Science
2019
|