Multi-stage models for the failure of complex systems, cascading disasters, and the onset of disease

Complex systems can fail through different routes, often progressing through a series of (rate-limiting) steps and modified by environmental exposures. The onset of disease, cancer in particular, is no different. Multi-stage models provide a simple but very general mathematical framework for studyin...

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Bibliographic Details
Main Author: Webster, A
Format: Journal article
Published: Public Library of Science 2019