Hypoxia-inducible factor 1 alpha-mediated RelB/APOBEC3B down-regulation allows hepatitis B virus persistence

<p><strong>Background and Aims:</strong> Therapeutic strategies against HBV focus, among others, on the activation of the immune system to enable the infected host to eliminate HBV. Hypoxia‐inducible factor 1 alpha (HIF1α) stabilization has been associated with impaired immune resp...

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Main Authors: Riedl, T, Faure-Dupuy, S, Rolland, M, Schuehle, S, Hizir, Z, Calderazzo, S, Zhuang, X, Wettengel, J, Lopez, MA, Barnault, R, Mirakaj, V, Prokosch, S, Heide, D, Leuchtenberger, C, Schneider, M, Heßling, B, Stottmeier, B, Wessbecher, IM, Schirmacher, P, McKeating, JA, Protzer, U, Durantel, D, Lucifora, J, Dejardin, E, Heikenwalder, M
Format: Journal article
Language:English
Published: Wolters Kluwer 2021