Functional human α7 nicotinic acetylcholine receptor (nAChR) generated from escherichia coli

Human Cys-loop receptors are important therapeutic targets. High-resolution structures are essential for rational drug design, but only a few are available due to difficulties in obtaining sufficient quantities of protein suitable for structural studies. Although expression of proteins in E. coli of...

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Bibliographic Details
Main Authors: Tillman, T, Alvarez, F, Reinert, N, Liu, C, Wang, D, Xu, Y, Xiao, K, Zhang, P, Tang, P
Format: Journal article
Language:English
Published: American Society for Biochemistry and Molecular Biology 2017