Variation in the TNF-alpha promoter region associated with susceptibility to cerebral malaria.

Tumour-necrosis factor-alpha (TNF-alpha) is believed to have an important role in the pathogenesis of severe infectious disease and fatal cerebral malaria is associated with high circulating levels of this cytokine. In a large case-control study in Gambian children we find that homozygotes for the T...

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Bibliographic Details
Main Authors: McGuire, W, Hill, A, Allsopp, C, Greenwood, B, Kwiatkowski, D
Format: Journal article
Language:English
Published: 1994