p56lck interacts via its src homology 2 domain with the ZAP-70 kinase.

p56lck, a member of the src family of protein tyrosine kinases, is an essential component in T cell receptor (TCR) signal transduction. p56lck contains a src homology 2 (SH2) domain found in a number of proteins involved in intracellular signaling. SH2 domains have been implicated in protein-protein...

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Bibliographic Details
Main Authors: Duplay, P, Thome, M, Hervé, F, Acuto, O
Format: Journal article
Language:English
Published: 1994