Characterization of an anti-fetal AChR monoclonal antibody isolated from a myasthenia gravis patient

We report here the sequence and functional characterization of a recombinantly expressed autoantibody (mAb 131) previously isolated from a myasthenia gravis patient by immortalization of thymic B cells using Epstein-Barr virus and TLR9 activation. The antibody is characterized by a high degree of so...

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Bibliographic Details
Main Authors: Saxena, A, Stevens, J, Cetin, H, Koneczny, I, Webster, R, Lazaridis, K, Tzartos, S, Vrolix, K, Nogales-Gadea, G, Machiels, B, Molenaar, P, Damoiseaux, J, De Baets, M, Simon-Keller, K, Marx, A, Vincent, A, Losen, M, Martinez-Martinez, P
Format: Journal article
Language:English
Published: Springer Nature 2017