Assessment of serum-free cortisol levels in patients with adrenocortical carcinoma treated with mitotane: a pilot study.

OBJECTIVE: Mitotane treatment in adrenocortical carcinoma (ACC) results in unreliable measurement of serum total cortisol (TC) levels because of an elevation in corticosteroid-binding globulin (CBG). DESIGN: The use of a newly-developed serum-free cortisol (FC) assay was assessed to investigate the...

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Bibliographic Details
Main Authors: Alexandraki, K, Kaltsas, G, le Roux, C, Fassnacht, M, Ajodha, S, Christ-Crain, M, Akker, SA, Drake, WM, Edwards, R, Allolio, B, Grossman, AB
Format: Journal article
Language:English
Published: 2010