Asparagine and aspartate hydroxylation of the cytoskeletal ankyrin family is catalyzed by factor-inhibiting hypoxia-inducible factor.

Asparagine and aspartate hydroxylation of the cytoskeletal ankyrin family is catalyzed by factor-inhibiting hypoxia-inducible factor.

Factor-inhibiting hypoxia-inducible factor (FIH) catalyzes the β-hydroxylation of an asparagine residue in the C-terminal transcriptional activation domain of the hypoxia inducible factor (HIF), a modification that negatively regulates HIF transcriptional activity. FIH also catalyzes the hydroxylati...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों:	Yang, M, Ge, W, Chowdhury, R, Claridge, T, Kramer, H, Schmierer, B, McDonough, M, Gong, L, Kessler, B, Ratcliffe, P, Coleman, M, Schofield, C
स्वरूप:	Journal article
भाषा:	English
प्रकाशित:	2011

समान संसाधन

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Posttranslational hydroxylation of ankyrin repeats in IkappaB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH).
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Self-hydroxylation of the splicing factor lysyl hydroxylase, JMJD6
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Oxygenase-Catalyzed Desymmetrization of N,N-Dialkyl-piperidine-4-carboxylic Acids
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Asparagine reduces the risk of schizophrenia: a bidirectional two-sample mendelian randomization study of aspartate, asparagine and schizophrenia
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प्रकाशित: (2024-04-01)

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द्वारा: Brewitz, L, और अन्य
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Small-molecule active pharmaceutical ingredients of approved cancer therapeutics inhibit human aspartate/asparagine-β-hydroxylas
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प्रकाशित: (2014)

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द्वारा: Markolovic, S, और अन्य
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Structure-based prediction of asparagine and aspartate degradation sites in antibody variable regions.
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Oxygenase-catalyzed ribosome hydroxylation occurs in prokaryotes and humans.
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Factor inhibiting hypoxia-inducible factor (FIH) and other asparaginyl hydroxylases.
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