CDC4/FBXW7 and the 'just enough' model of tumourigenesis

There is good evidence to show that cancer-causing mutations are not always simple gain- and loss-of-function changes. One example is the APC gene, where the combination of mutations produces a 'just-right' level of Wnt signalling. A recent article by Berger and colleagues posited a '...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Davis, H, Tomlinson, I
التنسيق: Journal article
اللغة:English
منشور في: 2012