CDC4/FBXW7 and the 'just enough' model of tumourigenesis

CDC4/FBXW7 and the 'just enough' model of tumourigenesis

Taispeáin leaganacha eile (1)

There is good evidence to show that cancer-causing mutations are not always simple gain- and loss-of-function changes. One example is the APC gene, where the combination of mutations produces a 'just-right' level of Wnt signalling. A recent article by Berger and colleagues posited a '...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoirí:	Davis, H, Tomlinson, I
Formáid:	Journal article
Teanga:	English
Foilsithe / Cruthaithe:	2012

Míreanna comhchosúla

CDC4/FBXW7 and the 'just enough' model of tumourigenesis.
de réir: Davis, H, et al.
Foilsithe / Cruthaithe: (2012)

Loss of CDC4/FBXW7 in Gastric Carinoma
de réir: A. N. Milne, et al.
Foilsithe / Cruthaithe: (2010-01-01)

Cancer‐associated FBXW7 loss is synthetic lethal with pharmacological targeting of CDC7
de réir: Joseph S. Baxter, et al.
Foilsithe / Cruthaithe: (2024-02-01)

The F-box protein Cdc4/Fbxw7 is a novel regulator of neural crest development in <it>Xenopus laevis</it>
de réir: Hartley Rebecca S, et al.
Foilsithe / Cruthaithe: (2010-01-01)

FBXW7/hCDC4 controls glioma cell proliferation <it>in vitro </it>and is a prognostic marker for survival in glioblastoma patients
de réir: Hagedorn Martin, et al.
Foilsithe / Cruthaithe: (2007-02-01)

PADI4 and tumourigenesis
de réir: Fang Kehua, et al.
Foilsithe / Cruthaithe: (2010-03-01)

Functional analysis of cancer-causing FBXW7 mutations
de réir: Davis, HL
Foilsithe / Cruthaithe: (2012)

Just enough unix /
de réir: 200556 Andersen, Paul K.
Foilsithe / Cruthaithe: (2000)

Just enough UNIX /
de réir: 200556 Andersen, Paul K.
Foilsithe / Cruthaithe: (1997)

Just enough UNIX /
de réir: 200556 Andersen, Paul K.
Foilsithe / Cruthaithe: (2006)

Just enough UNIX /
de réir: 200556 Andersen, Paul K.
Foilsithe / Cruthaithe: (2003)

The Role of FBXW7 in Gynecologic Malignancies
de réir: Riccardo Di Fiore, et al.
Foilsithe / Cruthaithe: (2023-05-01)

FBXW7 mutations typically found in human cancers are distinct from null alleles and disrupt lung development
de réir: Davis, H, et al.
Foilsithe / Cruthaithe: (2011)

FBXW7 mutations typically found in human cancers are distinct from null alleles and disrupt lung development.
de réir: Davis, H, et al.
Foilsithe / Cruthaithe: (2011)

Investigation of the atypical FBXW7 mutation spectrum in human tumours by conditional expression of a heterozygous propellor tip missense allele in the mouse intestines
de réir: Davis, H, et al.
Foilsithe / Cruthaithe: (2014)

Investigation of the atypical FBXW7 mutation spectrum in human tumours by conditional expression of a heterozygous propellor tip missense allele in the mouse intestines.
de réir: Davis, H, et al.
Foilsithe / Cruthaithe: (2014)

Introduction to the Special Feature: Just Complex Enough for Understanding; Just Simple Enough for Communication
de réir: C. S. Holling
Foilsithe / Cruthaithe: (1999-12-01)

REC: Just Radical Enough
de réir: Myin Erik, et al.
Foilsithe / Cruthaithe: (2015-06-01)

Sugar tags and tumourigenesis
de réir: Usha eNagarajan, et al.
Foilsithe / Cruthaithe: (2015-11-01)

The role of E-cadherin in low-grade ductal breast tumourigenesis.
de réir: Roylance, R, et al.
Foilsithe / Cruthaithe: (2003)

FBXW7 influences murine intestinal homeostasis and cancer, targeting Notch, Jun, and DEK for degradation.
de réir: Babaei-Jadidi, R, et al.
Foilsithe / Cruthaithe: (2011)

Just enough C/C++ programming /
de réir: 398408 Lecky-Thompson, Guy W.
Foilsithe / Cruthaithe: (2008)

Mostly Windows with just enough DOS /
de réir: 431547 Schildt, Herbert
Foilsithe / Cruthaithe: (1994)

Just enough AutoCAD 2007 /
de réir: 319983 Omura, George
Foilsithe / Cruthaithe: (2006)

Fbxw7 controls angiogenesis by regulating endothelial Notch activity.
de réir: Nanae Izumi, et al.
Foilsithe / Cruthaithe: (2012-01-01)

The paradoxical role of nucleoporins in tumourigenesis
Foilsithe / Cruthaithe: (2022-03-01)

Colorectal tumourigenesis in carriers of the APC I1307K variant: lone gunman or conspiracy?
de réir: Sieber, O, et al.
Foilsithe / Cruthaithe: (2003)

FBXW7 in breast cancer: mechanism of action and therapeutic potential
de réir: Siyu Chen, et al.
Foilsithe / Cruthaithe: (2023-09-01)

Recent Insight on Regulations of FBXW7 and Its Role in Immunotherapy
de réir: Liangliang Xing, et al.
Foilsithe / Cruthaithe: (2022-06-01)

Clinical significance of FBXW7 loss of function in human cancers
de réir: Jingyi Fan, et al.
Foilsithe / Cruthaithe: (2022-03-01)

FBXW7 and the Hallmarks of Cancer: Underlying Mechanisms and Prospective Strategies
de réir: Wenyue Shen, et al.
Foilsithe / Cruthaithe: (2022-04-01)

Editorial: Just Enough of a Shared Vision
de réir: Peter Murray
Foilsithe / Cruthaithe: (2019-02-01)

BONE MORPHOGENETIC PROTEIN (BMP) PATHWAY DYSREGULATION SUBVERTS ONCOGENE INDUCED SENESCENCE MECHANISMS IN THE SERRATED PATHWAY OF TUMOURIGENESIS
de réir: Boitsova, T, et al.
Foilsithe / Cruthaithe: (2013)

Investigation of the role of ASPP2 in tumourigenesis
de réir: Tordella, L
Foilsithe / Cruthaithe: (2012)

Cyclins and their related proteins in pituitary tumourigenesis.
de réir: Muşat, M, et al.
Foilsithe / Cruthaithe: (2010)

Role of JMJD6 in Breast Tumourigenesis.
de réir: Coralie Poulard, et al.
Foilsithe / Cruthaithe: (2015-01-01)

Neural stem cell derived tumourigenesis
de réir: Francesca Froldi, et al.
Foilsithe / Cruthaithe: (2015-01-01)

Pivotal Role of FBXW4 in Glioma Progression and Prognosis
de réir: Kun Chen, et al.
Foilsithe / Cruthaithe: (2024-01-01)

Characterisation of the effect of FBXW7 mutations in normal and malignant colonic tissue
de réir: Chan, DKH
Foilsithe / Cruthaithe: (2023)

FBXW7 in gastrointestinal cancers: from molecular mechanisms to therapeutic prospects
de réir: Wanqing Wang, et al.
Foilsithe / Cruthaithe: (2024-12-01)