Mutations of the light meromyosin domain of the beta-myosin heavy chain rod in hypertrophic cardiomyopathy.

Familial hypertrophic cardiomyopathy (HCM) is caused by mutations in 9 sarcomeric protein genes. The most commonly affected is beta-myosin heavy chain (MYH7), where missense mutations cluster in the head and neck regions and directly affect motor function. Comparable mutations have not been describe...

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Bibliografische gegevens
Hoofdauteurs: Blair, E, Redwood, C, de Jesus Oliveira, M, Moolman-Smook, J, Brink, P, Corfield, V, Ostman-Smith, I, Watkins, H
Formaat: Journal article
Taal:English
Gepubliceerd in: 2002