Transcriptional interference perturbs the binding of Sp1 to the HIV-1 promoter.
Transcriptional interference between adjacent genes has been demonstrated in a variety of biological systems. To study this process in RNA polymerase II (pol II) transcribed genes we have analysed the effect of transcription on tandem HIV-1 promoters integrated into the genome of HeLa cells. We show...
Autori principali: | Greger, I, Demarchi, F, Giacca, M, Proudfoot, N |
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Natura: | Journal article |
Lingua: | English |
Pubblicazione: |
1998
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