Individual crypt genetic heterogeneity and the origin of metaplastic glandular epithelium in human Barrett's oesophagus.

OBJECTIVES: Current models of clonal expansion in human Barrett's oesophagus are based upon heterogenous, flow-purified biopsy analysis taken at multiple segment levels. Detection of identical mutation fingerprints from these biopsy samples led to the proposal that a mutated clone with a select...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Leedham, S, Preston, S, McDonald, SA, Elia, G, Bhandari, P, Poller, D, Harrison, R, Novelli, MR, Jankowski, J, Wright, N
Format: Journal article
Język:English
Wydane: 2008