Elevated pontine and putamenal GABA levels in mild-moderate Parkinson disease detected by 7 tesla proton MRS

Background Parkinson disease (PD) is characterized by the degeneration of nigrostriatal dopaminergic neurons. However, postmortem evidence indicates that the pathology of lower brainstem regions, such as the pons and medulla, precedes nigral involvement. Consistently, pontomedullary damage was impli...

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Bibliografski detalji
Glavni autori: Emir, U, Tuite, P, Öz, G
Format: Journal article
Jezik:English
Izdano: Public Library of Science 2012