Branched tetrahydrofuran alpha,alpha-disubstituted-delta-sugar amino acid scaffolds from branched sugar lactones: a new family of foldamers?

Efficient SN2 ring closure of open chain trihydroxytriflates-in which the leaving group is on a primary carbon adjacent to a quaternary centre-provides access to tetrahydrofurans with branched carbon chains from branched carbohydrate lactones; the first examples of a new class of branched chain tetr...

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Bibliographic Details
Main Authors: Simone, M, Soengas, R, Newton, C, Watkin, D, Fleet, G
Format: Journal article
Language:English
Published: 2005