Branched tetrahydrofuran alpha,alpha-disubstituted-delta-sugar amino acid scaffolds from branched sugar lactones: a new family of foldamers?
Efficient SN2 ring closure of open chain trihydroxytriflates-in which the leaving group is on a primary carbon adjacent to a quaternary centre-provides access to tetrahydrofurans with branched carbon chains from branched carbohydrate lactones; the first examples of a new class of branched chain tetr...
| Main Authors: | , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2005
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| Summary: | Efficient SN2 ring closure of open chain trihydroxytriflates-in which the leaving group is on a primary carbon adjacent to a quaternary centre-provides access to tetrahydrofurans with branched carbon chains from branched carbohydrate lactones; the first examples of a new class of branched chain tetrahydrofuran α,α-disubstituted-δ-sugar amino acid scaffolds are described. © 2005 Elsevier Ltd. All rights reserved. |
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